Background and Aim: Congenital hypothyroidism is one of the most common preventable causes of mental retardation in the world the irreversible complications of which can be prevented with timely diagnosis and treatment by the fourth week. This study determined the prevalence of risk of congenital hypothyroidism in Torbat-E-Heydarieh.

Material and Methods: In this cross-sectional study according to the public screening of new burns for congenital hypothyroidism in the Torbat-E-Heydariyeh in 1390. Infants of 3 to 5day sold were monitored in allareascovered by the School of Medical Sciences Torbat-E-Heydariyeh. Heel blood samples were collected and filtered using What-man BFC180paper for serum TSH levels, and they were then assessed. The data were analyzed with T-test, two- way ANOVA and chi-square using the SPSS19. P<0.05 was considered as significant.

Results: 2500 newborns were screened, 62.5% of them were infants. Incidence of congenital hypothyroidism was 1.2inevery 1000live births respectively (p<0.03). Serum TSH levels in 92.1% of infants with hypothyroidism were 5 to 9.9mu/Lit and 5.26% of infants10 to19.9mu/Lit and the 2.63% of infants were over 20mu/Lit.

Conclusion: In accordance with the high rate of transient hypothyroidism in the monitored population, it is better in the original sampling, amount of T3, T4 were assessed for reducing false positive results.