Journal of Torbat Heydariyeh University of Medical Sciences
مجله دانشگاه علوم پزشکی تربت حیدریه
jmsthums
Medical Sciences
http://jms.thums.ac.ir
1
admin
2716-9669
2716-9669
10.61882/jmsthums
fa
jalali
1403
9
1
gregorian
2024
12
1
12
3
online
1
fulltext
fa
اثر تمرینات ورزشی بر آدروپین، آدیپولین و شاخصهای مقاومت به انسولین در زنان بزرگسال دارای اضافهوزن و چاق: یک مرور نظاممند و فراتحلیل
The effect of exercise training on adropin, adiponillin, and insulin resistance indices in overweight and obese adult women: A Systematic Review and Meta-Analysis
تخصصي
Special
پژوهشي
Research
<span style="line-height:115%"><span style="tab-stops:.05pt 1.7pt"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin"">زمینه و هدف:</span></span></span></b><b> </b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">تمرینات ورزشی بهعنوان یک راهکار عملی نقش مهمی در افزایش آدروپین، آدیپولین و کاهش مقاومت به انسولین و پیشگیری از عوارض اضافهوزن دارند. لذا مطالعه حاضر باهدف تعیین اثر تمرینات ورزشی بر آدروپین، آدیپولین و شاخصهای مقاومت به انسولین در زنان بزرگسال دارای اضافهوزن و چاق انجام شد.</span></span></span></span></span><br>
<span style="line-height:115%"><span style="tab-stops:.05pt 1.7pt"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin"">روش­ ها:</span></span></span></b> <span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">جستجوی سیستماتیک مقالات انگلیسی و فارسی منتشرشده از پایگاههای اطلاعاتی</span></span></span><span style="font-family:Times New Roman;">PubMed<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%">، </span></span>Web of Science<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%">، </span></span>Scopus<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%">، </span></span>Sid</span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> و </span></span></span><span style="font-family:Times New Roman;">Magiran</span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> تا ژوئن سال 2024 انجام شد. تفاوت میانگین و فاصله اطمینان 95% (</span></span></span>CI<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">) با استفاده از مدل اثر تصادفی محاسبه شد. ناهمگونی با استفاده از آزمون (</span></span></span>I2<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">) و سوگیری انتشار با تحلیل بصری فونل پلات و آزمون </span></span></span>Egger<span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> بررسی شدند.</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""></span></span></span></span></span><br>
<span style="line-height:115%"><span style="tab-stops:.05pt 1.7pt"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin"">نتایج:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> درمجموع 9 مطالعه (با 10 مداخله) و 208 آزمودنی زن بزرگسال دارای اضافهوزن و چاق فراتحلیل شدند. نتایج نشان داد که تمرینات ورزشی سبب افزایش غیر معنادار آدروپین </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">]</span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:Times New Roman;">P</span>=0/139 </span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">،(0/534- الی 3/820) 0/378-=</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">[<span style="font-family:Times New Roman;">WMD</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">، آدیپولین</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">]</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">0/573</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:Times New Roman;">P</span>=</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">،(8/034- الی 14/674) 3/320=</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">[<span style="font-family:Times New Roman;">WMD</span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> و کاهش غیرمعنادار گلوکز </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">]</span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">P=0/005 </span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">،(12/291- الی 2/153-) 7/222-=</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">[<span style="font-family:Times New Roman;">WMD</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"Calibri",sans-serif"></span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">، انسولین </span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">]</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">0/154</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">P=</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">،(3/178- الی 0/503) 1/337-=</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">[<span style="font-family:Times New Roman;">WMD</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> و </span></span></span><span lang="AR-SA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">مقاومت به انسولین<b> </b></span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">]</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">0/254</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">P=</span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra"">،(0/181- الی 0/048) 0/067-=</span></span></span><span dir="LTR" style="font-size:12.0pt"><span style="line-height:115%">[<span style="font-family:Times New Roman;">WMD</span></span></span><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> نسبت به گروه کنترل در زنان بزرگسال دارای اضافهوزن و چاق شد.</span></span></span></span></span><br>
<span style="line-height:115%"><span style="tab-stops:.05pt 1.7pt"><b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Nazanin"">نتیجه­ گیری:</span></span></span></b><span lang="FA" style="font-size:12.0pt"><span style="line-height:115%"><span style="font-family:"B Mitra""> نتایج فراتحلیل نشان داد که تمرینات ورزشی سبب تغییر معنادار بر آدروپین، آدیپولین و شاخصهای مقاومت به انسولین در زنان بزرگسال دارای اضافهوزن و چاق نشد. تمرینات ورزشی نسبت به گروه کنترل اثر بهتری بر بهبود آدروپین، آدیپولین و شاخصهای مقاومت به انسولین ندارد.</span></span></span></span></span>
<div></div>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><i><span style="font-size:11.5pt">Background & Aim</span></i></b><i><span style="font-size:11.5pt">:</span></i> <span style="font-size:11.5pt">Exercise training, as a practical strategy, plays an important role in increasing adropin, adiponillin, reducing insulin resistance and preventing complications of overweight. Therefore, the present study aimed to determine the effect of exercise training on adropin, adiponillin, and insulin resistance indices in overweight and obese adult women.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><i><span style="font-size:11.5pt">Methods</span></i></b><b><span style="font-size:11.5pt">:</span></b><span style="font-size:11.5pt"> A systematic search was conducted for English and Farsi articles published in PubMed, Web of Science, Scopus, Sid and Magiran databases until June 2024. The mean difference and 95% confidence interval (CI) were calculated using a random effects model. Heterogeneity was assessed using the I2 test, and publication bias was evaluated through visual analysis of the funnel plot and Egger's test.</span></span></span></span></span><br>
<span style="font-size:11pt"><span style="line-height:normal"><span style="unicode-bidi:embed"><span style="font-family:"Times New Roman",serif"><b><i><span style="font-size:11.5pt">Results</span></i></b><b><span style="font-size:11.5pt">:</span></b> <span lang="EN" style="font-size:11.5pt">A total of 9 studies (10 interventions) and 208 </span><span style="font-size:11.5pt">overweight and obese </span><span lang="EN" style="font-size:11.5pt">adult female subjects were included in the meta-analysis. The results showed that exercise training had a non-significant effect on adropin [WMD=-0.387 (3.820 to -0.534) P=0.139], adipolin [WMD=3.320 (14.674 to -8.034) P=0.573], as well as a non-significant decrease in glucose [WMD=-7.222 (-2.153 to -12.291) P=0.005]</span><span style="font-size:11.5pt">, </span><span lang="EN" style="font-size:11.5pt">insulin [WMD=-1.337 (0.503 to -3.178) P=0.154] and insulin resistance [WMD=0.254 (0.048 to -0.181) P=-0.067] compared to the control group of </span><span style="font-size:11.5pt">overweight and obese </span><span lang="EN" style="font-size:11.5pt">adult women</span><span style="font-size:11.5pt">.</span></span></span></span></span><br>
<b><i><span style="font-size:11.5pt"><span style="line-height:150%"><span style="font-family:"Times New Roman",serif">Conclusion</span></span></span></i><span style="font-size:11.5pt"><span style="line-height:150%"><span style="font-family:"Times New Roman",serif">:</span></span></span></b><span style="font-size:11.5pt"><span style="line-height:150%"><span style="font-family:"Times New Roman",serif"> Our meta-analysis revealed that exercise training did not significantly improve adropin, adiponillin, and insulin resistance indices in overweight and obese adult women. Specifically, exercise training did not lead to a significant decrease in these indices compared to the control group.</span></span></span>
تمرین ورزشی, آدروپین, آدیپولین, مقاومت به انسولین, بزرگسال
Exercise Training, Adropin, Adipoline, Insulin Resistance, women, Adult
93
114
http://jms.thums.ac.ir/browse.php?a_code=A-10-1858-1&slc_lang=fa&sid=1
Taheri
A
اسماء
طاهری
a.taheri@scu.ac.ir
100319475328460014365
100319475328460014365
Yes
Shahid Chamran University of Ahvaz
دانشگاه شهید چمران اهواز
Moghadasi
M
مهرزاد
مقدسی
mehrzad.moghadasi@gmail.com
100319475328460014366
100319475328460014366
No
Islamic Azad University, Shiraz
دانشگاه آزاد اسلامی شیراز
ZAFARMAND
O
امید
ظفرمند
OMIDZAFARMAND2202@GMAIL.COM
100319475328460014367
100319475328460014367
No
University of Yasouj
دانشگاه یاسوج