Volume 11, Issue 1 (7-2023)
2023, 11(1): 75-83 |
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H Q, R S, A H, F M. The effect of topical prednisolone acetate 1% on the pupillary diameter and ocular pain after uncomplicated cataract
surgery in diabetic and non-diabetic patients. Journal title 2023; 11 (1) :75-83
URL: http://jms.thums.ac.ir/article-1-1176-en.html
URL: http://jms.thums.ac.ir/article-1-1176-en.html
1- Mashhad University of Medical Sciences, Mashhad, Iran
2- Department of Psychiatry and Community Health Nursing School of Nursing and Midwifery, Golestan University of Medical Sciences (GOUMS), Gorgan, IR
2- Department of Psychiatry and Community Health Nursing School of Nursing and Midwifery, Golestan University of Medical Sciences (GOUMS), Gorgan, IR
Abstract: (1005 Views)
Background & Aim: Cataract surgery is the most common intraocular procedure in theworld. Trauma during surgery causes an inflammatory response in the eye. This studyaimed to determine the effect of 1% prednisolone acetate topical drops on pupil dilation and pain after uncomplicated cataract surgery in diabetic and non-diabetic patients.
Methods: In this double-blind clinical trial study, 80 patients with cataracts participated. First, the patients were divided into 2 diabetic and non-diabetic groups, and then each group was randomly assigned to 2 intervention and control groups. Intervention groups received 1% prednisolone acetate drops 4 times, 24 hours before surgery, and artificial tear drops were used for the control group. Tearing, pain, photophobia, itching, foreign body sensation and horizontal pupil diameter were compared between 4 groups using chi-square, independent t tests and analysis of variance.
Results: Prednisolone Acetate 1% topical drops had a significant effect on pupil dilation (P=0.03). Postoperative photophobia in patients receiving prednisolone drops in non-diabetic patients was significantly lower than in the control group (p=0.001). The severity of postoperative itching in patients receiving prednisolone drops in both non-diabetic (p=0.006) and diabetic (p=0.02) groups was lower than their control groups. The amount of pain reduction in the non-diabetic intervention group was higher than the other groups (p=0.04).
Conclusion: The results of this study show that the topical drug prednisolone acetate 1% can be used before cataract surgery as an auxiliary drug to maintain intraoperative dilatation in diabetic and non-diabetic patients and reduce photophobia, pain and itching after surgery.
Methods: In this double-blind clinical trial study, 80 patients with cataracts participated. First, the patients were divided into 2 diabetic and non-diabetic groups, and then each group was randomly assigned to 2 intervention and control groups. Intervention groups received 1% prednisolone acetate drops 4 times, 24 hours before surgery, and artificial tear drops were used for the control group. Tearing, pain, photophobia, itching, foreign body sensation and horizontal pupil diameter were compared between 4 groups using chi-square, independent t tests and analysis of variance.
Results: Prednisolone Acetate 1% topical drops had a significant effect on pupil dilation (P=0.03). Postoperative photophobia in patients receiving prednisolone drops in non-diabetic patients was significantly lower than in the control group (p=0.001). The severity of postoperative itching in patients receiving prednisolone drops in both non-diabetic (p=0.006) and diabetic (p=0.02) groups was lower than their control groups. The amount of pain reduction in the non-diabetic intervention group was higher than the other groups (p=0.04).
Conclusion: The results of this study show that the topical drug prednisolone acetate 1% can be used before cataract surgery as an auxiliary drug to maintain intraoperative dilatation in diabetic and non-diabetic patients and reduce photophobia, pain and itching after surgery.
Type of Study: Research |
Subject:
Special
Received: 2023/05/15 | Accepted: 2023/07/18 | Published: 2023/08/8
Received: 2023/05/15 | Accepted: 2023/07/18 | Published: 2023/08/8
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