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jmsthums 2025, 13(1): 1-11 |
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M K, E S, M M, F M. Effect of ethanolic and aqueous extracts of leaves and branches of Calotropis procera on common warts. jmsthums 2025; 13 (1) :1-11
URL: http://jms.thums.ac.ir/article-1-1382-en.html
URL: http://jms.thums.ac.ir/article-1-1382-en.html
1- Non-communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
2- Psychosocial Trauma Research Center, Ilam University of Medical Sciences, Ilam, Iran
3- Faculty of Medicine, Department of Dermatology, Ilam University of Medical Sciences, Ilam, Iran
4- Clinical Research Development Unit, Mostafa Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
2- Psychosocial Trauma Research Center, Ilam University of Medical Sciences, Ilam, Iran
3- Faculty of Medicine, Department of Dermatology, Ilam University of Medical Sciences, Ilam, Iran
4- Clinical Research Development Unit, Mostafa Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran
Abstract: (214 Views)
Background & Aim: : Skin warts are benign proliferative lesions that occur at any age. Current treatments for plantar warts have a high cost and low efficiency. The aim of this study was to investigate the therapeutic efficacy of ethanolic and aqueous extracts of the leaves and branches of Calotropis procera on common warts.
Methods: This study included patients who referred to a dermatologist for treatment of warts in the foot region and had at least 3 warts. The first wart was treated with aqueous extract, the second with ethanolic extract and the third with conventional salicylic acid treatment (reference treatment) for one month with a daily dose of one drop of all three therapeutic solutions separately on the specified warts. To compare the differences between the studied groups, analysis of variance with repeated measures was used. Data analysis was performed using SPSS software and the error level was considered to be 5%.
Results: This experimental study was performed on 41 patients (19 males and 22 females). The results of the test showed that the variables of the type of treatment method were significant at the level of 5% error (F=12.416, P<0.05). The lowest level of wart diameter was observed for the ethanolic extract of Calotropis procera. Also, none of the interaction effects of the type of treatment method were significant with the variables of age (F=0.634, P>0.05) and gender (F=0.431, P>0.05).
Conclusion: Alcoholic extract of Calotropis procera can be a therapeutic method for foot warts with minimal side effects.
Methods: This study included patients who referred to a dermatologist for treatment of warts in the foot region and had at least 3 warts. The first wart was treated with aqueous extract, the second with ethanolic extract and the third with conventional salicylic acid treatment (reference treatment) for one month with a daily dose of one drop of all three therapeutic solutions separately on the specified warts. To compare the differences between the studied groups, analysis of variance with repeated measures was used. Data analysis was performed using SPSS software and the error level was considered to be 5%.
Results: This experimental study was performed on 41 patients (19 males and 22 females). The results of the test showed that the variables of the type of treatment method were significant at the level of 5% error (F=12.416, P<0.05). The lowest level of wart diameter was observed for the ethanolic extract of Calotropis procera. Also, none of the interaction effects of the type of treatment method were significant with the variables of age (F=0.634, P>0.05) and gender (F=0.431, P>0.05).
Conclusion: Alcoholic extract of Calotropis procera can be a therapeutic method for foot warts with minimal side effects.
Type of Study: Applicable |
Subject:
Special
Received: 2024/12/22 | Accepted: 2025/04/19 | Published: 2025/06/30
Received: 2024/12/22 | Accepted: 2025/04/19 | Published: 2025/06/30
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