Volume 9, Issue 3 (1-2022)                   jms 2022, 9(3): 13-21 | Back to browse issues page

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M S, SH N, V V, Z G. Effect of period of high intensity interval training on serum IL-4 in schizophrenic male. jms. 2022; 9 (3) :13-21
URL: http://jms.thums.ac.ir/article-1-989-en.html
1- M.Sc. in Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.
2- Assistant Professor in Exercise Physiology, Department of Sport Sciences, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran
3- University of Sistan and Baluchestan
4- Zahedan university of Medical Sciences
Abstract:   (505 Views)
Background & Aim: Today schizophrenia has a high incident in population and is developing among men and women. The purpose of present study is to evaluate effect of 8 weeks of HIIT on serum IL-4 in male schizophrenic patients.
Methods: Present study is semi-experimental one with pre-posttest design. 28 male patients with schizophrenia with age range of 25-45 years old were divided into two groups of control and Intervention randomly. HIIT were performed for 8 weeks (3 sessions in a week with 70-85% maximum heart rate). Each session consisted of RAST protocol included 35 meter running for 6 repetitions. At the end of 8 weeks, after 12 hours fasting blood sampling was gathered and serum IL-4 content were assessed using ELISA method. Data were analyzed through SPSS 24 while using ANCOVA and paired t test at P<0.05.
Results: Significant increase in IL-4 levels in Intervention group compared to control were observed (p=0.029). In addition, pre-posttest changes for IL-4 were significant in Intervention group (p=0.005). however, it was not significant in control (p= 0.51).
Conclusion: Regular HIIT might mitigate vital impact on serum IL-4 level increase in male schizophrenic patients through improvement in inflammatory status as a useful and healthy method in attenuation of psychotic disorders such as schizophrenia.
 
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Type of Study: Research | Subject: Special
Received: 2021/09/6 | Accepted: 2022/01/12 | Published: 2022/02/5

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